2024 Rome, Italy

I-007 Mahmoud Ali
mastering upset plots: a comprehensive tutorial for effective data visualization in pharmacometrics and drug development
Wednesday 10:20-11:50
I-008 Nikolaos Alimpertis
Leveraging the Finite Absorption Time (F.A.T.) Concept for Advancing PBPK Modeling and Pharmacometric structural models: Moving MIDD to Model Informed Drug Development and Assessment (MIDDA)
Wednesday 10:20-11:50
I-012 Innocent Asiimwe
The Applied Pharmacometrics Training Program – Year 3 Sustainability
Wednesday 10:20-11:50
I-014 Sally Babiker
Dose rationale for bedaquiline in paediatric patients with multi drug-resistant tuberculosis
Wednesday 10:20-11:50
I-017 Pavel Balazki
User-friendly and Quality-Controlled PBPK/QSP M&S Framework in R for Regulatory Submissions using Open Systems Pharmacology Software
Wednesday 10:20-11:50
I-079 Giuseppe De Nicolao
A mixed effect multi-funnel model for country surveillance of antibiotic resistance: evidence from the WHO GLASS dashboard
Wednesday 10:20-11:50
I-088 Giovanni Di Veroli
Bridging the gap between secondary pharmacology and hemodynamics findings via Quantitative Systems modelling
Wednesday 10:20-11:50
I-101 Alan Faraj
Model-based approaches to prospectively power pediatric pharmacokinetic trials with limited sample size
Wednesday 10:20-11:50
I-110 Sophie Fischer-Holzhausen
Development of a gestational Physiologically Based Kinetic model to predict rat dam and fetus exposure in PK-Sim/MoBi
Wednesday 10:20-11:50
I-112 Thomas Frank
Automating pharmacometrics reporting using R Markdown
Wednesday 10:20-11:50
II-033 Niels Hendrickx
Evaluation of treatment effects in genetic ataxias using SARA score modelling: comparison of multiple trial designs by a large trial simulation framework
Wednesday 15:20-16:50
II-037 Sara Carolina Henriques
Unveiling the Potential of Cmax ƒ2 Factor Applied to Pilot Bioavailability/Bioequivalence Studies
Wednesday 15:20-16:50
II-043 Andrew Hooker
Generating uncertainty estimates in empirical forest plots
Wednesday 15:20-16:50
II-045 Ziheng Hu
Choice of Exposure Metric in Exposure-Response Modeling
Wednesday 15:20-16:50
II-051 Ibrahim Ince
Qualification of the Open Systems Pharmacology PBPK modeling Platform for simulation of transporter Drug-Drug-Interactions
Wednesday 15:20-16:50
II-068 Daniel Kaschek
Using the M3 Method in Exploratory Plots and in NCA
Wednesday 15:20-16:50
II-069 Csaba Katai
An asymptotic description of a basic FcRn-regulated clearance mechanism and its implications for PBPK modelling of large antibodies
Wednesday 15:20-16:50
II-097 Valentin Legras
Sunburst Plots for Analyzing the Impact of Drugs on CRS
Wednesday 15:20-16:50
III-011 John Maringwa
Assessing Approaches for Handling Missing Precision Measures Issue in Model-Based Meta Analysis (MBMA)
Thursday 09:50-11:20
III-029 Zeyar Mohammed Ali
Evaluation of extrapolation potential of IMPRES-M, a non-parametric Impulse-Response Modeling framework when applied to pharmacokinetic profiles of different dosing frequencies
Thursday 09:50-11:20
III-065 Mariana Pereira
Etravirine's Pharmacokinetics Explored: PBPK Modeling and DDI Analysis with Efavirenz for Cancer Treatment
Thursday 09:50-11:20
III-074 Cesar Pichardo
The International Society of Pharmacometrics’ Special Interest Group on Quantitative Systems Pharmacology (ISoP QSP SIG): Recent Developments and Future Vision
Thursday 09:50-11:20
III-083 Anne Ravix
Numerical validation of Tucuxi, a promising new Bayesian adaptation tool
Thursday 09:50-11:20
III-093 Matthew Riggs
bbr.bayes: An Open-Source Tool to Facilitate an Efficient, Reproducible Bayesian Workflow Using NONMEM
Thursday 09:50-11:20
III-108 Andrew Santulli
nonmem2mrgsolve: An R package for Automated NONMEM to mrgsolve Translation
Thursday 09:50-11:20
IV-010 Erik Sjögren
Absorption, Bioavailability, and Immunogenicity after Subcutaneous Administration: Evaluation of a Subcutaneous Platform within the Open Systems Pharmacology framework
Thursday 15:00-16:30
IV-034 Florencia Tettamanti
Predicting Progression Free Survival from Measurable Residual Disease (MRD) in Chronic Lymphocytic Leukemia (CLL)
Thursday 15:00-16:30
IV-065 Peter Velickovic
Translational pharmacology and dose rationale for imatinib and doramapimod as a host-directed therapy for the treatment of pulmonary tuberculosis
Thursday 15:00-16:30
IV-069 Laura Villain
Considerations for the application of PBPK to optimize drug therapies in special populations: The Open Systems Pharmacology solutions
Thursday 15:00-16:30
IV-087 Mélanie Wilbaux
How to handle population pharmacokinetics modeling in the context of a regulatory submission for a compound already well-characterized in other settings? A case-study with nivolumab in urothelial cancer.
Thursday 15:00-16:30
IV-089 Insa Winzenborg
Uncovering Bias in Exposure-Response Relationships: Investigating the Impact of Exposure Calculation for Irregular Dosing Regimens
Thursday 15:00-16:30
IV-090 Daniel Wojtyniak
Influential factors on the type I error rate in pharmacometrics models using individual model averaging or standard approach
Thursday 15:00-16:30
IV-099 Koichiro Yoneyama
Impact of Imbalanced Baseline Responses among Dose Levels in the Exposure-Response Analysis by Nonlinear Mixed-Effect Modeling
Thursday 15:00-16:30
IV-114 Jochen Zisowsky
Target-mediated drug disposition of monoclonal antibody binding to plasma soluble target: some insights from PBPK/PD and popPK/PD approaches
Thursday 15:00-16:30