2024 Rome, Italy

I-001 Noha Abdelgawad
Pharmacokinetic Modelling of Rifampicin, Isoniazid, Pyrazinamide, and Linezolid in Central Nervous System: Insights from a Rabbit Model of Tuberculosis Meningitis
Wednesday 10:20-11:50
I-011 Arkadiusz Adamiszak
Do critically ill patients undergoing continuous renal replacement therapy require ceftaroline dosage adjustments? Ceftaroline PopPK model and dosage simulations with probability of target attainment analysis based on retrospective data.
Wednesday 10:20-11:50
I-013 Romain Aubry
Translational PKPD modelling of ceftazidime/avibactam for treatment of carbapenemase-producing Klebsiella pneumoniae in the persistently neutropenic rabbit pneumonia model
Wednesday 10:20-11:50
I-015 Salma Bahnasawy
Applying PKPD modelling to evaluate the impact of plasma proteins in time-kill experiments; does the protein binding matter?
Wednesday 10:20-11:50
I-043 Nils Bundgaard
Model informed dose projection for SAB-176 using a joint time-to-event modeling approach in high-risk (HR) patients infected with Influenza
Wednesday 10:20-11:50
I-044 Nils Bundgaard
Framework for Polyclonal Antibody Drug Development: Integrating Trial Data and Literature Models
Wednesday 10:20-11:50
I-048 Jose Miguel Calderin Miranda
Population pharmacokinetic analysis of isoniazid in plasma and cerebrospinal fluid from adults with HIV-associated tuberculosis meningitis
Wednesday 10:20-11:50
I-068 Emmanuelle Comets
Modelling the dynamics of bacterial colonisation in a murine model of Urinary Tract Infections
Wednesday 10:20-11:50
I-096 Yin Edwards
Pharmacokinetics/pharmacodynamics and exposure-response modelling of VH3810109 (N6LS) in antiretroviral therapy-naïve adults with HIV-1 from the Phase IIa BANNER Study
Wednesday 10:20-11:50
I-103 Aneeq Farooq
A pharmacometric model assessing the synergistic effect of bacteriophage-polymyxin combination therapy in a clinical multidrug-resistant K. pneumoniae isolate in vitro.
Wednesday 10:20-11:50
I-116 María García-Cremades
Predictors of treatment outcomes in children with rifampicin-resistant tuberculosis: a global individual patient data meta-analysis
Wednesday 10:20-11:50
II-015 Silvia Grandoni
Do differences in PK defeat similarities in immune system in non-human primates? Pharmacokinetic modelling of standard of care antitubercular drugs in marmosets
Wednesday 15:20-16:50
II-016 Meng Gu
Evaluating empirical dose-response relationships and dosing strategies of bacteriophage therapy using a mechanism-based modeling approach
Wednesday 15:20-16:50
II-026 Felix Hammann
Informing BOHEMIA cluster randomized controlled trial ivermectin dose selection in healthy participants in Kenya
Wednesday 15:20-16:50
II-028 Miriam Happ
Quantifying the impact of infection on murine antibiotic exposure in the framework of non-conventional treatment modalities within the FAIR study
Wednesday 15:20-16:50
II-035 Rasmus Henninger
Preclinical population pharmacokinetic modelling of skin target site exposure of DNDI-0690 and DNDI-6148 in the treatment of cutaneous leishmaniasis
Wednesday 15:20-16:50
II-050 Marjorie Imperial
Step-Wise Population Pharmacokinetic Modeling Approach to Characterize Complex Absorption of Lenacapavir Following SC Administration in Healthy Participants
Wednesday 15:20-16:50
II-054 Van der Feltz Isabella
Delpazolid population pharmacokinetics and pharmacodynamics in patients with pulmonary tuberculosis
Wednesday 15:20-16:50
II-065 Woojin Jung
Predicting lung exposure of intramuscular niclosamide as an antiviral agent against COVID-19 using power-law-based pharmacokinetic modeling
Wednesday 15:20-16:50
II-072 Allan Kengo
Population pharmacokinetic analysis of the drug interaction between ritonavir-boosted atazanavir and rifampicin
Wednesday 15:20-16:50
II-078 Simon Koele
Population pharmacokinetics and exposure-response of BTZ-043 for the treatment of tuberculosis.
Wednesday 15:20-16:50
II-090 Anna Largajolli
Clinical Model-Based Meta-Analysis applied to Vaccine Development for SARS-CoV-2 Variants
Wednesday 15:20-16:50
II-095 Donghwan Lee
Beyond One-Size-Fits-All: Tailoring Teicoplanin Regimens for Normal Renal Function Patients with Population Pharmacoki-netics and Monte-Carlo Simulation
Wednesday 15:20-16:50
II-103 Yu-Jou Lin
Model-informed once-daily dosing strategy for children, adolescents and adults for bedaquiline and delamanid
Wednesday 15:20-16:50
II-109 Xuanlin Liu
Viral dynamic modeling of nirmatrelvir against SARS-CoV-2 in an in vitro infection model
Wednesday 15:20-16:50
III-027 Laurynas Mockeliunas
Model-based assessment of early bactericidal activity of rifampicin in combination with meropenem plus amoxicillin/clavulanate among adults with rifampicin-resistant pulmonary tuberculosis
Thursday 09:50-11:20
III-032 Felix Müller
Understanding variability in microdialysis measurements: introducing a combined calibration approach for piperacillin and tazobactam in LPS-induced septic piglets
Thursday 09:50-11:20
III-048 Amaury O'Jeanson
Data-driven model selection for model-informed precision dosing: a case study with vancomycin
Thursday 09:50-11:20
III-049 Ochuko Orherhe
Pharmacometric modelling to describe pharmacokinetics and exposure-response of ivermectin in adolescent patients infected with Trichuris trichiura
Thursday 09:50-11:20
III-072 Anh Duc Pham
Population plasma and tissue pharmacokinetics of linezolid in healthy volunteers and septic patients
Thursday 09:50-11:20
III-087 Quentin Renou
External evaluation of a population pharmacokinetic (POP-PK) model of Cabotegravir HIV-1-infected patients treated with long-acting Cabotegravir/Rilpivirine (LA CAB-RPV)
Thursday 09:50-11:20
III-088 Juan Eduardo Resendiz Galvan
What is the effective concentration of dolutegravir? A pharmacokinetic/pharmacodynamic analysis.
Thursday 09:50-11:20
III-109 Raphaël Saporta
Pharmacokinetic-pharmacodynamic modelling to characterize the time-course of meropenem effect in vivo on bacteria with high MIC
Thursday 09:50-11:20
III-111 Sharon Sawe
Population pharmacokinetics of delamanid in adults treated for rifampicin-resistant tuberculosis: effect of pregnancy.
Thursday 09:50-11:20
III-113 Carmine Schiavone
Understanding Population Heterogeneity in Vaccine-induced Immunity: A Mechanistic Model for Immune Fingerprinting
Thursday 09:50-11:20
III-114 Verena Schöning
Total and unbound flucloxacillin population pharmacokinetics in patients with Staphylococcus aureus bloodstream infection
Thursday 09:50-11:20
III-116 Clarisse Schumer
Building a model from comparison of SARS-CoV-2 viral dynamics model proposed since 2020: what are the main differences?
Thursday 09:50-11:20
IV-004 Jérémy Seurat
Macrophage-induced reduction of bacteriophage density limits the efficacy of pulmonary phage therapy
Thursday 15:00-16:30
IV-017 Britta Steffens
Pharmacometric analysis to explore moxidectin treatment with and without albendazole in Trichuris trichiura-infected adolescents
Thursday 15:00-16:30
IV-020 Oleg Stepanov
Utilizing the AZD7442 Model for Accelerated New Drug Development: Pharmacokinetic Insights Across Infectious Disease Prevention and Passive Immunization
Thursday 15:00-16:30
IV-063 Alberto Vegas
Modelling & simulation of biomarkers during anti-HIV monotherapy treatment
Thursday 15:00-16:30
IV-064 Nieves Velez de Mendizabal
A circular PK/PD/PK model explains the exposure of bulevirtide and bile salts in adult patients with chronic hepatitis D
Thursday 15:00-16:30
IV-066 Bharadwaj Vemparala
Modeling the influence of antiretroviral treatment initiation time on post-treatment control of HIV infection
Thursday 15:00-16:30
IV-068 Diego Vera-Yunca
Assessing clinical outcomes of nosocomial pneumonia patients with a pharmacometric multistate model
Thursday 15:00-16:30
IV-073 Jannik Vollmer
Combined population PK modelling of cefepime and enmetazobactam to characterize their individual and combined PK from the phase 1 to 3 studies
Thursday 15:00-16:30
IV-075 Thanakorn Vongjarudech
Evaluation of QT Prolongation During Bedaquiline Treatment Using a Time-Varying Tuberculosis-Specific Correction Factor (QTcTBT)
Thursday 15:00-16:30
IV-080 Shayne Watson
Population PK and PKPD modeling of TBA-7371 in Healthy Adults and Adults with tuberculosis
Thursday 15:00-16:30
IV-088 Francis Williams Ojara
Population pharmacokinetic characterisation of plasma-to-breast milk transfer of lamivudine and subsequent infant exposure through breast milk
Thursday 15:00-16:30
IV-104 Hinojal Zazo Gómez
Dosing evaluation of ceftazidime/avibactam in intensive care unit patients based on pharmacokinetic-pharmacodinamic (PK/PD) modelling and simulation.
Thursday 15:00-16:30