2024 Rome, Italy

I-018 Asma Baliouze
Exposure-Response Analysis of Centanafadine Sustained Release Tablets in Adults with Attention-Deficit/Hyperactivity Disorder
Wednesday 10:20-11:50
I-032 Monir Bertayli
PK-PD model of morphine, pregabalin and their combination to assess the opioid-sparing effect
Wednesday 10:20-11:50
I-061 Lu Chen
Time-dependent pharmacokinetics of hydromethylthionine mesylate (HMTM), a tau aggregation inhibitor, in healthy volunteers and patients with Alzheimer's Disease
Wednesday 10:20-11:50
I-113 Aline Fuchs
Human dose prediction approach for a therapeutic monoclonal antibody for a CNS indication inferred using preclinical data including target occupancy
Wednesday 10:20-11:50
II-005 Mohamed Gewily
Quantitative comparisons of Progressive Supranuclear Palsy rating scales versions using Item Response Theory modeling
Wednesday 15:20-16:50
II-039 Maria Patricia Hernandez Mitre
Population pharmacokinetics of olanzapine and quetiapine in critically ill adults with delirium
Wednesday 15:20-16:50
II-049 Silvia Illamola
Population analysis of blood-brain barrier heterogeneity and correlation with imaging characteristics in individuals with central nervous system malignancies.
Wednesday 15:20-16:50
III-007 Victor Mangas-Sanjuan
Pharmacometric characterization of the reserpine-induced fibromyalgia model in rats to support a model-informed dosing regimen strategy for alternative disease status conditions
Thursday 09:50-11:20
III-062 Noel Patson
Natural disease progression model with transition probabilities to describes the continuum of Alzheimer’s disease
Thursday 09:50-11:20
III-066 Carlos Perez-Ruixo
A Mechanism-Based PK/PD Model for Posdinemab (JNJ-63733657), a Humanized Monoclonal Antibody Targeting pTau, in healthy and Alzheimer’s Disease Subjects
Thursday 09:50-11:20
III-094 Elena Righetti
A mechanistic model of pure and lipid-mediated alpha-synuclein aggregation to advance therapeutic strategies against Parkinson’s disease
Thursday 09:50-11:20
III-101 Chiara Roversi
Integrated Population PK and PBPK Modelling Approaches of IAMA-6 Plasma Concentrations following Oral, Intraperitoneal and Intravenous Administrations in Three Different Preclinical Species for First in Human Dose Prediction
Thursday 09:50-11:20
IV-023 ming sun
Bayesian PBPK modeling for acyclovir dose optimization for treating viral encephalitis
Thursday 15:00-16:30
IV-056 Marloes van Leuken
A population pharmacokinetic model of N,N-dimethyltryptamine administered through continuous intravenous infusion in healthy smokers and non-smokers
Thursday 15:00-16:30
IV-106 Mengxu Zhang
Exploring the contribution of brain metabolism in mechanistic understanding of Kp,uu,BBB – A case study for remoxipride
Thursday 15:00-16:30