2022 Ljubljana, Slovenia

I-05 Monir Bertayli
Dose determination of morphine to investigate the analgesic effects of morphine and pregabalin in healthy subjects using a combined NONMEM model
Wednesday 09:45-11:15
I-14 Alessandro Di Deo
Evaluation of the pharmacokinetics of tideglusib in congenital and childhood myotonic dystrophy type 1 using Bayesian priors
Wednesday 09:45-11:15
I-16 Alan Faraj
A joint ketamine and esketamine exposure-response model of MADRS score in major depressive disorder to enable informed trial design for candidate drugs with similar mode of action
Wednesday 09:45-11:15
I-19 Iztok Grabnar
Pharmacokinetic-pharmacodynamic model of fentanyl sedation in children with severe acute bronchiolitis
Wednesday 09:45-11:15
I-21 Benjamin Guiastrennec
A Bounded Integer Approach to Evaluate AIMS Score for Austedo in Patients with Tardive Dyskinesia
Wednesday 09:45-11:15
I-22 Seiichi Hayato
Population pharmacokinetics and exposure-response analyses of amyloid PET SUVr and plasma biomarkers Aβ42/40 ratio and p-tau181 for lecanemab in subjects with early Alzheimer’s disease
Wednesday 09:45-11:15
I-33 Vincent Madelain
Multicompartmental PKPD model to inform active exposure of nucleic acid therapeutic candidate in CNS disease
Wednesday 09:45-11:15
I-34 Parsshava Mehta
Application of interspecies PBPK modeling to characterize BBB permeability and assess target site exposure-response using levetiracetam as model drug
Wednesday 09:45-11:15
I-36 Anna Mishina
Simulation of Rituximab and Natalizumab biomarker efficacy using simplified QSP model of B- and T- lymphocyte dynamics in Multiple Sclerosis
Wednesday 09:45-11:15
I-38 Chiara Nicolò
MS TreatSim: A clinical trial simulator for Relapsing-remitting Multiple Sclerosis
Wednesday 09:45-11:15
I-46 Anne Ravix
Population pharmacokinetic study of lacosamide in children and adults with epilepsy
Wednesday 09:45-11:15
I-63 Xiaofeng Wang
Exposure–response modelling of aripiprazole and brexpiprazole in adults and adolescents with schizophrenia to support extrapolation of efficacy in adolescents
Wednesday 09:45-11:15