| I-05 Monir Bertayli Dose determination of morphine to investigate the analgesic effects of morphine and pregabalin in healthy subjects using a combined NONMEM model Wednesday 09:45-11:15 |
| I-14 Alessandro Di Deo Evaluation of the pharmacokinetics of tideglusib in congenital and childhood myotonic dystrophy type 1 using Bayesian priors Wednesday 09:45-11:15 |
| I-16 Alan Faraj A joint ketamine and esketamine exposure-response model of MADRS score in major depressive disorder to enable informed trial design for candidate drugs with similar mode of action Wednesday 09:45-11:15 |
| I-19 Iztok Grabnar Pharmacokinetic-pharmacodynamic model of fentanyl sedation in children with severe acute bronchiolitis Wednesday 09:45-11:15 |
| I-21 Benjamin Guiastrennec A Bounded Integer Approach to Evaluate AIMS Score for Austedo in Patients with Tardive Dyskinesia Wednesday 09:45-11:15 |
| I-22 Seiichi Hayato Population pharmacokinetics and exposure-response analyses of amyloid PET SUVr and plasma biomarkers Aβ42/40 ratio and p-tau181 for lecanemab in subjects with early Alzheimer’s disease Wednesday 09:45-11:15 |
| I-33 Vincent Madelain Multicompartmental PKPD model to inform active exposure of nucleic acid therapeutic candidate in CNS disease Wednesday 09:45-11:15 |
| I-34 Parsshava Mehta Application of interspecies PBPK modeling to characterize BBB permeability and assess target site exposure-response using levetiracetam as model drug Wednesday 09:45-11:15 |
| I-36 Anna Mishina Simulation of Rituximab and Natalizumab biomarker efficacy using simplified QSP model of B- and T- lymphocyte dynamics in Multiple Sclerosis Wednesday 09:45-11:15 |
| I-38 Chiara Nicolò MS TreatSim: A clinical trial simulator for Relapsing-remitting Multiple Sclerosis Wednesday 09:45-11:15 |
| I-46 Anne Ravix Population pharmacokinetic study of lacosamide in children and adults with epilepsy Wednesday 09:45-11:15 |
| I-63 Xiaofeng Wang Exposure–response modelling of aripiprazole and brexpiprazole in adults and adolescents with schizophrenia to support extrapolation of efficacy in adolescents Wednesday 09:45-11:15 |
